Pyrrolo[1,2-c]imidazolediones

Details Pyrrolo[1,2-c]imidazolediones Pyrrolo[1,2-c]imidazolediones

1973-11-01

1976-04-06

Love, Ethel G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602472R, 260268C, 26029388, 424248, 424250, 424273, C07D 4932

Patent

active

039489337

ABSTRACT:
5,6,7,7A-Tetrahydro-1H-pyrrolo[1,2-c]imidazole-1,3-(2H)-diones of the formula ##SPC1##
In which R is phenyl, substituted phenyl or cyclohexyl, X is oxygen or sulfur and R.sub.1 is hydroxy, lower alkoxy, di-lower alkylamino-lower alkoxy, an --NR.sub.2 R.sub.3 radical wherein R.sub.2 and R.sub.3 each independently represents hydrogen, lower alkyl, hydroxy-lower alkyl, phenyl, substituted phenyl, benzyl or together with the adjacent nitrogen atom represent a pyrrolidino, a piperidino, a morpholino or a piperazino radical. The compounds of the invention are useful as C.N.S. depressants and in particular as tranquilizing and anxiolytic agents.

REFERENCES:
rogers et al., J.A.C.S. - Aug. 1941, pp. 2190-2191.

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