Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1991-03-26
1992-07-14
Bond, Robert T.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
540496, 540560, A61K 3155, C07D47514
Patent
active
051303019
ABSTRACT:
Novel 4H-pyrrolo[1,2-a]thieno[2,3-f][1,4]diazepine which are usable as a medicinal product and correspond to the general formula (I): ##STR1## in which: R.sub.1, R.sub.2, R.sub.3 and R.sub.4 have the same meaning as given in the specification.
These compounds, as well as their physiologically tolerable salts, may be used in therapy, in particular in the treatment of disorders linked to hypoxemia and to certain metabolic disorders.
REFERENCES:
Novel Convenient Synthesis of 1,4-Diazepines, 6-alkoxy-5,6-Dihydro-4H-Pyrrolo [1,2-a] Thieno [3,2-f]-4-Diazepine-4-Ones, S. Rault et al., Heterocycles (1979) 12 (8) pp. 1009-1011.
Pyrrolo [1,2-a] Thieno [3,2-f]-1,4-Diazepines, Novel Synthesis and X-Ray Analysis, S. Rault et al., Tetrahedron Letters (1979)N.degree. 7 pp. 643-644.
Synthesis of 4H-Pyrrolo [1,2-a] Thieno [3,2-f] [1,4] Diazepines, H. Fujimori et al., Journal of Heterocyclic Chemistry (1977) 14 (2) pp. 235-240.
Boulouard Michel
Devissaguet Michelle
Guardiola Beatrice
Rault Sylvain
Robba Max
Adir et Compagnie
Bond Robert T.
Hueschen Gordon W.
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