Pyrrolidones with anti-HIV activity

Details Pyrrolidones with anti-HIV activity Pyrrolidones with anti-HIV activity

2003-10-21

2009-02-24

Saeed, Kamal A (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S422000, C514S423000, C546S276400, C548S518000, C548S530000

Reexamination Certificate

active

07495016

ABSTRACT:
The present invention relates to inhibition of viruses, e.g., HIV using pyrrolidones and compounds related to pyrrolidones. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhibit HIV in a cell; as well as to methods of prophylaxis, and therapy related to HIV infection and related disease states such as AIDS.

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Keller, Thomas H., et al.; “Synthesis and Structure-Activity Relationship ofN-Arylrolipram Derivatives as Inhibitors of PDE4 Isozymes”;Chem. Pharm. Bull.2001 pp. 1009-1017 vol. 49 No. 8.
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