Pyrrolidone-5,5-diphosphonic acids

Details Pyrrolidone-5,5-diphosphonic acids Pyrrolidone-5,5-diphosphonic acids

1976-02-20

1977-07-05

Ore, Dale R.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

252499, 252175, 252381, 2603265FN, 423555, 424DIG6, 424 57, A61K 31675

Patent

active

040340864

ABSTRACT:
Pyrrolidone-5,5-diphosphonic acids having the formula ##STR1## wherein R is a member selected from the group consisting of hydrogen and alkyl having from 1 to 6 carbon atoms; as well as their water-soluble salts. The pyrrolidone-5,5-diphosphonic acids are excellent sequestering agents especially for alkaline earth metal ions. They are stabilizers for percompounds and are useful in the delaying of the setting times for gypsum. In addition, the compounds are useful as cosmetic preparations such as toothpastes and mouthwashes where they prevent formation of tartar and plaque and are useful in therapy in the treatment of diseases related to the abnormal deposition or dissolution of difficultly soluble calcium salts in the animal body.

REFERENCES:
patent: 3968220 (1976-07-01), Mamalis et al.
patent: 3968222 (1976-07-01), Drabek et al.

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