Pyrrolidone-2 compounds and their use for central analgesic acti

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

548550, 546268, 546275, 546281, 546261, 546208, C07D207273, A61K 3140

Patent

active

049607880

ABSTRACT:
Compounds of formula ##STR1## (wherein R, R.sub.1, R.sub.2, R.sub.3 and n have the meanings reported in the specification), their salts with pharmaceutically acceptable acids, process for their preparation and pharmaceutical compositions containing them are described.
The compounds of formula I have a remarkable analgesic activity.

REFERENCES:
patent: 2496163 (1949-01-01), Jacobsen
patent: 4320137 (1982-03-01), Paioni
patent: 4525476 (1985-06-01), Batler et al.
patent: 4670456 (1987-06-01), Weber et al.
patent: 4767759 (1988-08-01), Weber et al.
patent: 4833140 (1989-05-01), Weber et al.

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