Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...
Patent
1997-10-30
1999-10-19
Bernhardt, Emily
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitrogen attached directly or indirectly to the purine ring...
544372, 514252, C07D24102
Patent
active
059691387
ABSTRACT:
Since a compound represented by general formula (1), its pharmaceutically acceptable salt and a hydrate of the pharmaceutically acceptable salt have high antipsychotic activity, they may be used as an active ingredient for preparation of an antipsychotic. ##STR1## Also provided are an optical resolution method of the above compound and an intermediate for preparation of the compound.
REFERENCES:
patent: 4547504 (1985-10-01), Fabre et al.
patent: 4767759 (1988-08-01), Weber et al.
patent: 5538985 (1996-07-01), Iizuka et al.
Patent Abstracts of Japan, vol. 096, No. 002, Feb. 29, 1996 & JP 07252219A (Mitsui Toatsu Chemicals, Inc.), Oct. 3, 1985, *Abstract*.
Burt et al, Proc. Nat. Acad. Sci USA, "Dopamine Receptor Binding in the Corpus Striatum of Mammalian Brain", vol. 72, No. 11, pp. 4655-4659, 1975.
Vilner et al, Multiple Sigma and PCP Receptor Ligands: Mechanisms for Neuromodulation and Neuroprotection?, Characterization of Sigma-Like Binding Sites of NB41A3, S-20Y, and N1E-115 Neuroblastomas, C6 Glioma, and NG108-15 Neuroblastoma-Glioma Hybrid Cells: Further Evidence for Sigma-2 Receptors, pp. 341-353, 1992.
Horikomi Kazutoshi
Iizuka Hajime
Mita Naruyoshi
Miwa Takaichi
Nagase Hiroshi
Bernhardt Emily
Mitsui Chemicals Inc.
LandOfFree
Pyrrolidinone derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Pyrrolidinone derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pyrrolidinone derivatives will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2057132