Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1988-09-26
1990-09-25
Hollrah, Glennon H.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
546152, 546243, 548469, C07D20726, A61K 3140
Patent
active
049594826
ABSTRACT:
A novel class of pyrrolidin-2-one and piperidin-2-one compounds in which the nitrogen atom is bonded to an oxyphenyl radical haivng tertiary-alkyl and tri-methylsilyl substituents. The compounds posses anti-inflammatory, immunomodulatory, analgesic and anti-pyretic activity and they may be combined with excipients to provide formulations which are useful in treating arthritis and conditions associated with that disease.
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K. F. Swingle et al.; "Anti-Inflammatory and Anti-Rheumatic Drugs", vol. III: Chapter 4, entitled Anti-Inflammator Activity of Antioxidants; CRC Press, Inc., K. D. Rainsford, Editor.
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Biofor, Ltd.
Hollrah Glennon H.
Molasky W. Joseph
Trinh Ba K.
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