Pyrrolidineacetic acid esters

Details Pyrrolidineacetic acid esters Pyrrolidineacetic acid esters

1976-11-15

1979-03-13

Daus, Donald G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424274, C07D20726

Patent

active

041442466

ABSTRACT:
Lower alkyl 2-oxo-4-phenyl-1-pyrrolidineacetic acid esters which are useful as pharmacological agents, especially cognition activators, are disclosed. They can be produced by reacting 4-phenyl-2-pyrrolidinone with a lower alkyl haloacetate in the presence of a strong base.

REFERENCES:
merck Index-9th Ed., Merck & Co., Rahway, N. J., 1976, fig. 7289.
C. F. Koelsch et al., "Synthesis of Methyl-6-phenyl-3-methyl-3-azapimelate", Journal of Organic Chemistry, vol. 21, 1956, p. 1211.
March, Advanced Organic Chemistry, 1968, p. 340.
Mindus, P. et al., Actapsychiat. Scand (1976), 54, pp. 150-160.

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