Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-03-28
2006-03-28
Bernhardt, Emily (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S218000, C514S254010, C540S575000, C544S364000, C544S372000
Reexamination Certificate
active
07019008
ABSTRACT:
A compound of Formula (I):wherein:R1is C1-6alkyl, benzyl, or (CH2)n—C(O)NH2; wherein the benzyl may be unsubstituted or substituted by one or two C1-6alkyl, halogen, C1-6alkoxy, or methylenedioxy groups;R2is benzimidazolyl, quinolinyl, benzofuranyl, napthyl, indolyl, benzothiophenyl, phenyl, furanyl, thienyl, or pyridyl substituted or unsubstituted by one, two or three halogen, C1-3alkyl, C1-3alkoxy, or methylenedioxy groups;X1and X2are independently hydrogen, halogen, C1-3alkyl, C1-3alkoxy, nitro, CF3, or CN;n is 1, 2, or 3;m is 1, 2 or 3;or a pharmaceutically acceptable salt thereof.
REFERENCES:
patent: 6265408 (2001-07-01), Forbes
Watson et al. Peptides, vol. 25, p. 1759-1766 (2004).
Dhanak et al. Annual Reports in Medicinal Chemistry, vol. 38, p. 99-11-(2003).
Dhanak Dashyant
Jin Jian
Knight Steven D.
Rivero Ralph A.
Sapienza Anthony
Bernhardt Emily
Gimmi Edward R.
Hall Linda
Lockenour Andrea V.
SmithKline Beecham Corporation
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