Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1990-03-13
1992-03-17
Ivy, C. Warren
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514255, 514340, 546275, 548568, 544408, 544336, A61K 3140, C07D20708
Patent
active
050968904
ABSTRACT:
Compounds of the formula ##STR1## wherein R, Y and R.sup.1 are as defined in the specification. These compounds are muscarinic receptor antagonists which are selective for smooth muscle muscarinic sites over cardiac muscarinic sites, and are useful in the treatment of diseases associated with altered motility on tone of smooth muscle, including irritable bowel syndrome, diverticular disease, urinary incontinence, oesophageal achalasia and chronic obstructive airways disease.
REFERENCES:
patent: 3403159 (1968-09-01), Pesson
patent: 4002766 (1977-01-01), Welstead
patent: 4242261 (1980-12-01), Cale
Cross Peter E.
MacKenzie Alexander R.
Bekelnitzky Seymore G.
Chang Celica
Ginsburg Paul H.
Ivy C. Warren
Pfizer Inc.
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