Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-07-23
1996-05-07
Wu, Shean C.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514826, 548517, 548524, 548527, C07D20714, A61K 3140
Patent
active
055147011
ABSTRACT:
This invention relates to pyrrolidine derivatives and pharmaceutically acceptable salts, their pharmaceutical compositions, and methods of use as thromboxane A.sub.2 antagonists and/or thromboxane A.sub.2 synthetase inhibitors in the treatment of thrombotic diseases, asthma or nephritis, e.g. of the formula: ##STR1## wherein R.sup.1 is thienyl(lower)alkyl, furyl(lower)alkyl or pyrrolyl(lower)alkyl.
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Hashimoto Masashi
Sawada Akihiko
Setoi Hiroyuki
Tanaka Hirokazu
Fujisawa Pharmaceutical Co. Ltd.
Kilby Scalzo Catherine
Wu Shean C.
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