Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-12-27
2009-12-29
Saeed, Kamal A (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S423000, C548S517000, C548S530000
Reexamination Certificate
active
07638550
ABSTRACT:
The invention describes new compounds derived from formula I pyrroles, methods for obtaining them and their application as drugs in pharmaceutical compositions for the treatment of cancer due to their inhibitory activity on certain histone deacetylases.
REFERENCES:
patent: WO 98/25896 (1998-06-01), None
patent: WO 2004/103968 (2004-12-01), None
patent: WO 2005/056004 (2005-06-01), None
Extended European Search Report dated Sep. 14, 2009 relating to European Patent Application No. 05850516.5.
Mai et al., “3-(4-Aroyl-1-methyl-1H-2-pyrroly1)-N-hydroxy-2-propenamides as a New Class of Synthetic Histone Deacetylase Inhibitors. 2. Effect of Pyrrole-C2 and/or -C4 Substitutions on Biological Activity”, J. Med. Chem. 2004, 47, pp. 1098-1109.
M. R. Graaf et al., “The risk of cancer in users of statins”, Journal of Clinical Oncology, vol. 22, No. 12, 2004, pp. 2388-2394.
R.T. Morrison et al., “Organic Chemistry”, Allyn and Bacon, Newton (Massachusetts, U.S.), XP002540604 Electrophilic Aromatic Substitution, p. 613.
Cossio Mora Fernando Pedro
Esteller Badosa Manel
Otaegui Ansa Dorleta
Zubia Olascoaga Aizpea
Ostrolenk Faber LLP
Saeed Kamal A
Shterengarts Samantha L
Universidad del Pais Vasco-Euskal Herriko Unibertsitatea (UPV-EH
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