Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1989-06-22
1992-01-21
Brust, Joseph P.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548531, 548532, 548535, A61K 3140, C07D207333
Patent
active
050828568
ABSTRACT:
Novel pyrrolecarboxylic acid derivatives represented by the following formula: ##STR1## where R.sup.1 is a hydrogen atom, an alkyl group of 5 to 25 carbon atoms or an alkenyl group of 5 to 25 carbon atoms, R.sup.2 is a hydrogen atom, a phenyl group or an optionally substituted alkyl group of 1 to 10 carbon atoms, and R.sup.3 is a hydrogen atom, an alkyl group of 5 to 25 carbon atoms or an alkenyl group of 5 to 25 carbon atoms, or pharmaceutically acceptable salts thereof are provided.
The compounds are highly effective in reducing the level of triglyceride or cholesterol in serum, and useful as an active ingredient of a pharmaceutical composition for treating hyperlipemia and arteriosclerosis.
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patent: 2500713 (1950-03-01), Sickels et al.
patent: 4194003 (1980-03-01), LaForest et al.
patent: 4560700 (1985-12-01), Schnettler et al.
patent: 4824958 (1989-04-01), Cetenko et al.
Hirata Mayumi
Inoue Shinya
Mitsuka Masayuki
Shinpuku Tetsuro
Shirasaka Tadashi
Brust Joseph P.
Mitsubishi Kasei Corporation
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