Pyrrole derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C546S279100

Reexamination Certificate

active

07598274

ABSTRACT:
Compounds of the formula (I), in which X, Y, Z and Ar have the meanings indicated in claim1, are inhibitors of Raf kinase and can be employed, inter alia, for the treatment of tumours

REFERENCES:
patent: 2004/0138269 (2004-07-01), Sun et al.
patent: 2004/0254186 (2004-12-01), Dean et al.
patent: 2008/0234270 (2008-09-01), Bannen et al.
patent: WO 03022833 (2003-03-01), None
Vippagunta et al., Crystalline solids, 2001, Advanced Drug Delivery Reviews, 48, pp. 3 and 18.
Wolff et al., Burger's Medicinal Chemistry and Drug Discovery, 1994, Wiley-lnterscience, Fifth Edition, vol. I: Principles and Practice, pp. 975-977.

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