Pyrrole derivative

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C548S571000

Reexamination Certificate

active

10474943

ABSTRACT:
A novel pyrrole derivative represented by the following formula (1) and a salt thereof:wherein R1means substituted alkenyl, etc.; R2means substituted benzoyl, etc.; and R3to R5each means hydrogen, alkyl, halogeno, etc. The derivative and salt have antidiabetic activity.

REFERENCES:
patent: 6310217 (2001-10-01), Lehr
patent: 98/05637 (1998-02-01), None
patent: 99/46244 (1999-09-01), None
patent: 01/53257 (2001-07-01), None
patent: 01/90067 (2001-11-01), None
Lehr, M., “Synthesis, Biological Evaluation, and Structure-Activity Relationships of 3-Acylindole-2-carboxylic Acids as Inhibitors of the Cytosolic Phospholipase A2”,J. Med. Chem.,vol. 40, pp. 2694 to 2705 (1997).

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