Pyrrole-carboxylic acids lumilysergol esters

Details Pyrrole-carboxylic acids lumilysergol esters Pyrrole-carboxylic acids lumilysergol esters

1972-03-07

1976-06-29

Rollins, Alton D.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424261, C07D45702

Patent

active

039667391

ABSTRACT:
Esters of 1-methyl-lumilysergol-10-methylether having the formula: ##SPC1##
Wherein R is selected from the group consisting of 2-furanoyl and the pyrrole group of the formula: ##SPC2##
Wherein Y is selected from the group consisting of hydrogen, lower alkyl having from 1 to 6 carbon atoms and phenyl; R.sub.1 is selected from the group consisting of hydrogen, methyl and carbonyl; R.sub.2 is selected from the group consisting of hydrogen, methyl, halogen and carbonyl, provided that only one of R.sub.1 and R.sub.2 can be carbonyl; R.sub.3 and R.sub.4 are selected from the group consisting of hydrogen, halogen, alkyl, alkoxy having from 1 to 6 carbon atoms and carboethoxy; the pharmaceutically acceptable addition salts thereof with an organic acid and a process for the preparation thereof. The compounds possess adrenolytic, hypotensive, sedative and antiserotoninic activities.

REFERENCES:
patent: 3155667 (1964-11-01), Camerino et al.
patent: 3228943 (1966-01-01), Bernardi et al.
patent: 3324133 (1967-06-01), Arcamone et al.
patent: 3341575 (1967-09-01), Fierce et al.
patent: 3418360 (1968-12-01), Schulz et al.
patent: 3461156 (1969-08-01), Fierce
patent: 3551571 (1970-12-01), Pachter et al.
patent: 3704233 (1972-11-01), Eich
Temperilli et al., in Chem. Abstr., vol. 76, col. 14782n, (Jan. 1972), (abstracting Germany 2,112,273, 10/71).
Vitali et al., in Chem. Abstr., vol. 74, col. 110172t, (May 1971).
Tohroyama et al., Chem. Abstr., vol. 71, col. 50354e, 1969.

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