Pyrrole-3-carboxylate cardiotonic agents

Details Pyrrole-3-carboxylate cardiotonic agents Pyrrole-3-carboxylate cardiotonic agents

1985-02-08

1985-12-24

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514343, 514422, A61K 3140, A61K 3144

Patent

active

045607001

ABSTRACT:
Pyrrole-3-carboxylates of the following general structure ##STR1## wherein R.sub.1 is a hydrogen or lower alkyl group; R.sub.2 is a 1 to 8 carbon atom alkyl group; and R.sub.3 is a hydrogen, lower alkyl, pyridyl, pyridylmethyl, pyrryl, pyrrylmethyl, thienyl, thienylmethyl or phenyl or benzyl optionally substituted with one or two lower alkyl, lower alkoxy, lower alkylthio, halogen, nitro, hydroxy, carboxy or cyano groups or with a methylenedioxy group.

REFERENCES:
patent: 4282242 (1981-08-01), Holland
patent: 4461906 (1984-07-01), Aschwanden et al.
Chem. Abst. 99:5464(h) (1983)-Magnus et al.
Chem. Abst. 100:209621(f) (1984)-Richter et al.

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