Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1977-02-25
1981-02-03
Lee, Mary C.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
26032647, 424274, C07D207337
Patent
active
042487846
ABSTRACT:
1-R.sub.1 -4-R.sub.4 -.alpha.,.alpha.,2,5-Tetramethylpyrrole-3-acetamides, useful as anti-secretory and anti-ulcer agents, are prepared by hydrolysis, in the presence of a dilute mineral acid, of a corresponding 1-R.sub.1 -4-R.sub.4 -.alpha.,.alpha.,2,5-tetramethylpyrrole-3-acetonitrile.
REFERENCES:
patent: 3247222 (1966-04-01), Lunsford
Herz et al., J. Org. Chem. vol. 24, pp. 201-204 (1959).
Thielheimer, Synthetic Methods of Organic Chemistry, vol. 12, 190, 250, vol. 13, 267, vol. 16, 263, 263a, vol 18, 249.
Gillet et al., Eur. J. Med. Chem. Chemica Therapeutica, vol. 11, 173-181 (1976).
Lambelin et al., Chem. Abs., vol. 79: 78604a (1973).
Bell Malcolm R.
Oesterlin Rudolf
Lee Mary C.
Sterling Drug Inc.
Webb William G.
Wyatt B. Woodrow
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