Pyrrolacetic amides having antiinflammatory activity

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

540480, 540524, 544 584, 544141, 544372, 546208, 546281, 548336, 548517, A61K 3140, C07D207323

Patent

active

048823490

ABSTRACT:
N-monosubstituted and N,N-disubstituted amides of the 1-methyl-5-p-toluoylpyrrole-2-acetic acid, which are active as antiinflammatory, analgesic, antipyretic, antisecretive and antitussive agents, are disclosed.
These amides are prepared by reacting an amine with an activated derivative of the 1-methyl-5-p-toluoylpyrrole-2-acetic-acid of formula ##STR1## where X is an activating group suitable for promoting the formation of an amide bond.

REFERENCES:
patent: 3952012 (1976-04-01), Carson
patent: 4070368 (1978-01-01), Carson
patent: 4200645 (1980-04-01), Goudie
patent: 4379793 (1983-04-01), Badia
patent: 4396626 (1983-08-01), Ward et al.
patent: 4434175 (1984-02-01), Doherty et al.
patent: 4521538 (1985-06-01), Baglioni
patent: 4568690 (1986-02-01), Baglioni
patent: 4571399 (1986-02-01), Bagioni
patent: 4578481 (1986-03-01), Baglioni
Abstract of Japan Application 0144256, Sep. 6, 1982, copy in 548-539.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Pyrrolacetic amides having antiinflammatory activity does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pyrrolacetic amides having antiinflammatory activity, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pyrrolacetic amides having antiinflammatory activity will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1426335

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.