Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1985-02-11
1989-11-21
Brust, Joseph Paul
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
540480, 540524, 544 584, 544141, 544372, 546208, 546281, 548336, 548517, A61K 3140, C07D207323
Patent
active
048823490
ABSTRACT:
N-monosubstituted and N,N-disubstituted amides of the 1-methyl-5-p-toluoylpyrrole-2-acetic acid, which are active as antiinflammatory, analgesic, antipyretic, antisecretive and antitussive agents, are disclosed.
These amides are prepared by reacting an amine with an activated derivative of the 1-methyl-5-p-toluoylpyrrole-2-acetic-acid of formula ##STR1## where X is an activating group suitable for promoting the formation of an amide bond.
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Abstract of Japan Application 0144256, Sep. 6, 1982, copy in 548-539.
Brust Joseph Paul
Sigma-Tau Industrie Farmaceutiche Riunite S.p.A
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