Pyroglutamic acid salts of t-butylamino-2,3-dihydroxypropane

Details Pyroglutamic acid salts of t-butylamino-2,3-dihydroxypropane Pyroglutamic acid salts of t-butylamino-2,3-dihydroxypropane

1977-02-09

1978-06-27

Daus, Donald G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260536, 424274, C07D20728

Patent

active

040974901

ABSTRACT:
Process for resolving enantiomers of 1-t-butylamino-2,3-dihydroxypropane using a pyroglutamic acid or a tartaric acid as resolving agent. The enantiomers of 1-t-butylamino-2,3-dihydroxypropane are useful in preparing .beta.-adrenergic blocking agents.

REFERENCES:
patent: 2528267 (1950-10-01), Dearborn et al.
patent: 2767213 (1956-10-01), Long
patent: 3116332 (1963-12-01), Sullivan
patent: 3255190 (1966-06-01), Broh-Kahn
patent: 3657237 (1972-04-01), Weinstock et al.
patent: 3862132 (1975-01-01), Irda et al.
patent: 3940406 (1976-02-01), Raabe et al.
Morrison et al.; Organic Chemistry, 3rd Ed., pp. 236-237 (1974).
Iliceto; Chem. Abs. vol. 49; pp. 929-930 (1955).

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