Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1981-09-16
1983-05-24
Lee, Mary C.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
544320, 544321, 546193, 546281, 546291, 546300, 546329, 546334, C07D40112, C07D40114
Patent
active
043850588
ABSTRACT:
This invention relates to 2-amino-4-pyrimidone derivatives, in which the amino group is substituted by a methylthioethyl, butyl or oxypropyl group bearing a terminal 4-dialkylaminomethyl-2-pyridyl group. The compounds have histamine H.sub.2 -antagonist activity. A specific compound of this invention is 2-[2-(4-dimethylaminomethyl-2-pyridylmethylthio)ethylamino]-5-(6-methyl-3- pyridylmethyl)-4-pyrimidone.
REFERENCES:
patent: 3932644 (1976-01-01), Durant et al.
patent: 4145546 (1979-03-01), Brown et al.
patent: 4154834 (1979-05-01), Brown et al.
patent: 4159329 (1979-06-01), Brown et al.
patent: 4218452 (1980-08-01), Brown et al.
patent: 4227000 (1980-10-01), Brown
patent: 4234588 (1980-11-01), Brown et al.
patent: 4250316 (1981-02-01), Algieri et al.
patent: 4255428 (1981-03-01), Brown et al.
Derwent Abs. 87537D (of Eur. Pat. 39989) (11/18/81).
Cooper David G.
Sach George S.
Foggio Richard D.
Keps Joan S.
Lee Mary C.
Lourie Alan D.
Smith Kline & French Laboratories Limited
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