Pyrimidoindole derivatives and processes for preparation thereof

Details Pyrimidoindole derivatives and processes for preparation thereof Pyrimidoindole derivatives and processes for preparation thereof

1992-02-18

1993-10-26

Bernhardt, Emily

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

514267, A61K 31505, C07D48704

Patent

active

052567800

ABSTRACT:
The present invention relates to novel pyrimidoindole derivatives and pharmaceutically acceptable salts thereof, in particular (+)-3,4-dihydro-5-methyl-2-[1-(5-methyl-1H-imidazol-4-yl)ethyl]pyrimido-[1 ,6-a]indol-1(2H)-one or its hydrochloride, useful for their 5-hydroxytryptamine antagonism.

REFERENCES:
patent: 4409224 (1983-10-01), Jirkovsky
patent: 4695578 (1987-09-01), Coates et al.

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