Pyrimido-quinoxalines having antiallergic properties

Details Pyrimido-quinoxalines having antiallergic properties Pyrimido-quinoxalines having antiallergic properties

1982-11-23

1984-09-18

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544250, A61K 31505, C07D48704

Patent

active

044724012

ABSTRACT:
A compound selected from the group consisting of pyrimido quinoxalines of the formula ##STR1## wherein R.sub.1 represents an alkoxy radical of 1 to 5 carbon atoms and R is selected from the group consisting of hydrogen, alkyl of 1 to 5 carbon atoms, --COR.sub.A, --CHO and ##STR2## R.sub.A is selected from the group consisting of alkyl of 1 to 6 carbon atoms, cycloalkyl of 3 to 6 carbon atoms, alkoxy of 1 to 5 carbon atoms and phenyl optionally substituted with at least one member of the group consisting of halogen, --NO.sub.2 and alkoxy of 1 to 3 carbon atoms and their non-toxic, pharmaceutically acceptable acid addition salts having antiallergic properties.

REFERENCES:
patent: 4127720 (1978-11-01), Juby et al.
patent: 4145419 (1979-03-01), Rowlands et al.
patent: 4151280 (1979-04-01), Rowlands et al.
patent: 4207318 (1980-06-01), Rowlands et al.
patent: 4254123 (1981-03-01), Ramm et al.
patent: 4279912 (1981-07-01), Rowlands et al.
patent: 4291033 (1981-09-01), Barnes et al.
patent: 4333934 (1982-06-01), Barnes et al.
Hermecz, et al., J. Chem. Soc., Perkin Trans 1 (1977), pp. 789-795.

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