Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system
Reexamination Certificate
2006-08-01
2006-08-01
Wilson, James O. (Department: 1623)
Organic compounds -- part of the class 532-570 series
Organic compounds
Four or more ring nitrogens in the bicyclo ring system
C514S262100
Reexamination Certificate
active
07084270
ABSTRACT:
Disclosed are novel pyrimido compounds that are selective inhibitors of both KDR an FGFR kinases and are selective against LCK. These compounds and their pharmaceutically acceptable salts are anti-proliferative agents useful in the treatment or control of solid tumors, in particular breast, colon, lung and prostate tumors. Also disclosed are pharmaceutical compositions containing these compounds and methods of treating cancer.
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Chen Yi
Daniewski Andrzej Robert
Harris William
Kabat Marek Michal
Liu Emily Aijun
Hoffman-La Roche Inc.
Johnston George W.
Rocha-Tramaloni Patricia S.
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