Pyrimido[6,1-a]isoguinoline-4-one derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system

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424251, C07D47104, A61K 31505

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active

044543190

ABSTRACT:
Pyrimido[6,1-a]isoquinoline-4-one derivatives of the formula: ##STR1## wherein R is C.sub.1 -C.sub.6 lower alkyl or 2-haloethyl (halo=Cl, Br or I) having antihypertensive activity.

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Maryanoff et al., J. Med. Chem., vol. 24(1), pp. 79-88, (01/81).
Maryanoff et al., Tetrahedron Letters, No. 28, pp. 2829-2832, (1982).
Nair et al., Chemical Abstracts, vol. 71, 101682v, (1969).
Kaneko et al., Chemical Abstracts, vol. 75, 36106b, (1971).
Lal et al., Chemical Abstracts, vol. 93, 220770m, (1980).

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