Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system
Patent
1982-06-01
1984-06-12
Lee, Mary C.
Organic compounds -- part of the class 532-570 series
Organic compounds
Four or more ring nitrogens in the bicyclo ring system
424251, C07D47104, A61K 31505
Patent
active
044543190
ABSTRACT:
Pyrimido[6,1-a]isoquinoline-4-one derivatives of the formula: ##STR1## wherein R is C.sub.1 -C.sub.6 lower alkyl or 2-haloethyl (halo=Cl, Br or I) having antihypertensive activity.
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Maryanoff et al., J. Med. Chem., vol. 24(1), pp. 79-88, (01/81).
Maryanoff et al., Tetrahedron Letters, No. 28, pp. 2829-2832, (1982).
Nair et al., Chemical Abstracts, vol. 71, 101682v, (1969).
Kaneko et al., Chemical Abstracts, vol. 75, 36106b, (1971).
Lal et al., Chemical Abstracts, vol. 93, 220770m, (1980).
Maryanoff Bruce E.
Molinari Albert J.
Lee Mary C.
McNeilab Inc.
Rivers Diana G.
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