Pyrimido[2,1-a]isoquinoline derivatives having antiallergy activ

Details Pyrimido[2,1-a]isoquinoline derivatives having antiallergy activ Pyrimido[2,1-a]isoquinoline derivatives having antiallergy activ

1977-09-21

1978-11-28

Coughlan, Jr., Paul M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

544247, 424251, C07D47114, C07D47122, A61K 31505

Patent

active

041277201

ABSTRACT:
A series of novel pyrimido[2,1-a]isoquinoline derivatives is provided for use as inhibitors of allergic reactions. The compounds exhibit antiallergy activity by both oral and parenteral routes of administration.

REFERENCES:
patent: 3792050 (1974-02-01), Hodson et al.
patent: 3847919 (1974-11-01), Knowles et al.
patent: 4017625 (1977-04-01), Kadin
patent: 4033961 (1977-07-01), Schwender et al.
patent: 4066766 (1978-03-01), Kadin
Cox, et al., Adv. in Drug Res., 5, 115-116 (1970).
Reimlinger, et al., Chem. Ber., 105, pp. 108-114 (1972).

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