Pyrimido[1,6-a]indoles, pharmaceutical preparations containing t

Details Pyrimido[1,6-a]indoles, pharmaceutical preparations containing t Pyrimido[1,6-a]indoles, pharmaceutical preparations containing t

1982-07-01

1984-04-24

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

42424857, 424251, 544 60, 544115, 544252, A61K 31505, C07D48704

Patent

active

044447680

ABSTRACT:
Novel amidines, especially N,N'-bridged carboxylic acid amidines of the general formula ##STR1## in which R.sub.1 represents an aromatic radical, R.sub.2 represents optionally esterified or amidated 1-carboxy-lower alkyl, Ph represents optionally substituted 1,2-phenylene and alk represents an aliphatic hydrocarbon radical separating the imino group from the methine group by from 1 to 3 carbon atoms, and their salts, have, inter alia, anti-inflammatory activity and can be used as active medicament substances in pharmaceutical preparations. They are produced according to methods known per se.

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Borisova, et al., Chemical Abstract, vol. 74, 22729z (1971).
Cohen, et al., Chemical Abstracts, vol. 75, 76387e (1971).
Bhandari, et al., Chemical Abstracts, vol. 75, 110202y (1971).
Borisova, et al., Chemical Abstracts, vol 77, 139850k (1972).
Gadaginmath, et al., Chemical Abstracts, vol. 83, 141748a (1975).
Artemenko, et al., Chemical Abstracts, vol. 86, 37493q (1977).

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