Pyrimido[1,6-a]indole derivatives

Details Pyrimido[1,6-a]indole derivatives Pyrimido[1,6-a]indole derivatives

1978-09-11

1981-12-22

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

424244, 4242484, 42424853, 42424856, 424251, 544 11, 544 96, 544115, 544245, 544252, 2602433, A61K 31505, C07D48704, C07D49114, C07D52100

Patent

active

043072348

ABSTRACT:
Pyrimido[1,6-a]indole derivatives characterized by having a substituted ethyl group at position 5 and optionally being further substituted at various positions on the pyrimido[1,6-a]indole nucleus are disclosed. The foregoing compounds are useful as antihypertensive agents in a mammal. Methods for their preparation also are disclosed.

REFERENCES:
patent: 3649626 (1972-03-01), von Strandtmann et al.
Borisova et al., "Chemical Abstracts", vol. 77 (1972), col. 139,850k.
Cattanach et al., "J. Chem. Soc. (C)", 1971, pp. 359-366.
Artemenko et al., "Chemical Abstracts", vol. 86 (1977), col. 37493q.
Borisova et al., "Chemical Abstracts", vol. 74 (1971), col. 22792z.

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