Pyrimidinyl or Pyridinyl alkenyl amine compounds

Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system

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546300, C07D21302, C07D23924

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active

055979190

ABSTRACT:
Patients susceptible to or suffering from central nervous system disorders are treated by administering an effective amount of an aryl substituted olefinic amine compound. Exemplary compounds are ((E)-4-(5-pyrimidinyl)-3-butene-1-amine, (E)-4-[3-(5-methoxypyridin)yl]-3-butene-1-amine. (E)-N-methyl-4-(5-pyrimidinyl)-3-butene-1-amine and (E)-N-methyl-4-[3 -(5-methoxypyrindin)yl]-3-butene-1-amine.

REFERENCES:
patent: 4786646 (1988-11-01), Guthrie et al.
patent: 4916145 (1990-04-01), Tilley et al.
patent: 4927838 (1990-05-01), Guthrie et al.
patent: 5212188 (1993-05-01), Caldwell et al.
Acheson, R. et al., J. Chem. Soc. Perkin Trans., vol. 2, pp. 579-585 (1980).
Erdtman, H. et al., Acta Chem. Scand., vol. 17, pp. 1717-1726 (1963).
Frank, W. et al., J. Org. Chem., vol. 43(15), pp. 2947-2949 (1978).
Gol'dfarb, Y. et al., J. Gen. Chem., USSR(Engl. Transl.), vol. 39, pp. 1071-1075 (1969).
Kamimura, H. et al., Agr. Biol. Chem., vol. 27, No. 10, pp. 684-688 (1963).
LaForge, F., JACS, vol. 50, pp. 2477-2483 (1928).
Malek, N. et al., J. Org. Chem., vol. 47, pp. 5395-5397 (1982).
Pinner, A., Chem. Ber., pp. 2861-2870 (1894).
Rondahl, L., Acta Pharm. Suec., vol. 14, No. 2, pp. 113-118 (1977).
Rondahl, L., Acta Pharm. Suec., vol. 13, pp. 229-234 (1976).
Sprouse, C. et al., Abstracts of Papers, p. 32, Coresta/TCRC, Joint Conference (1972).
Ashimori, A. et al., Chem. Pharm. Bull. vol. 38(9), pp. 2446-2458 (1990).

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