Pyrimidinone derivatives and their use in the treatment of...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C544S253000

Reexamination Certificate

active

07462620

ABSTRACT:
Compounds of formula (I):are inhibitors of the enzyme Lp-PLA2and are of use in therapy, in particular for treating atherosclerosis.

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U.S. Appl. No. 10/694,561, filed Oct. 2003, Hickey et al.
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Michael Lam, “Magic Molecules”, Pharmaceutical Executive, [online] Dec. 1, 2004, [retrieved on Jun. 9, 2005]. Retrieved from the internel, <http://www.pharmexec.com/pharmexec/article/articleDetail.jsp?id=140635&pageID=6>.
Keith E Suckling et al, Expert Opinion on Therapeutic Targets, , Jun. 2002, vol. 6, No. 3, pp. 309-314.
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