Pyrimidines and pyrazines useful as modulators of ion channels

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...

Reexamination Certificate

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Details

C514S256000, C514S252140, C514S269000

Reexamination Certificate

active

07858786

ABSTRACT:
The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.

REFERENCES:
patent: 6414149 (2002-07-01), Chu-Moyer et al.
patent: 6844347 (2005-01-01), Schnidler et al.
patent: 7323464 (2008-01-01), Davis et al.
patent: 2003/0199526 (2003-10-01), Choquette et al.
patent: 2005/0110416 (2005-03-01), Wilson et al.
patent: 2005/0277654 (2005-12-01), Maynard et al.
patent: 00/59510 (2000-10-01), None
patent: WO 2004092123 (2004-10-01), None
patent: 2005/040135 (2005-05-01), None
patent: 2005/058876 (2005-06-01), None
patent: 2005/110416 (2005-11-01), None
patent: WO 2006039325 (2006-04-01), None
patent: 2006/071762 (2006-07-01), None
Almeida et. al., Neurotherapeutics 4(1), 88-96, 2007.
Ekberg et al.,, The International Journal of Biochemistry & Cell Biology, 38, 2006-2010, 2006.
Markman et al, Journal of Pain, 7(15), 538-547, 2007.
Krivopalov et al., Khimiya Geterotsiklicheskikh Soedinenii (1983), (9), 1222-6, 1983; CA 100: 22633, 1984.
Darmanin et al. Bioorganic & Medicinal Chemistry Letters (2001), 11(24), 3133-3136.
Database Chemcats Chemical Abstracts Service, Columbus, Ohio, US' XP002397395 retrieved from STN Accessopm Mp/ 2005:432837, 2005:432417, 2005:431047, 2005:430868, 2005:430523, and 2005: 421395 & “ChemBridge Screening Library” Jan. 12, 2005.
Database Chemcats Chemical Abstracts Service, Columbus, Ohio, US' XP002397389 retrieved from STN Accession No. 2004:1976992, 2004:1976991, 2004:1976990, 2004:1976987 & “ChemDiv, Inc. Product Library” Apr. 25, 2003 (Mar. 3, 2003).

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