Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1987-10-23
1988-09-27
Goldberg, Jerome D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514275, A61K 31505
Patent
active
047742496
ABSTRACT:
The pyrimidine derivatives of formula I ##STR1## wherein R.sup.1 is naphthyl, substituted naphthyl or substituted phenyl; R.sup.2 is hydrogen or lower alkoxy; and A is an optionally present ethylene or 1,3-propylene, and wherein the diaminopyridine group has the exo-configuration when A is present, are described. These compounds are useful as antibacterial agents, antimalarial agents and antitumor agents, and can be used in combination with sulfonamides in the control of bacterial infections.
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Kompis et al., Chem. Abstract 88-152540F.
Chem. Abstract 51-15607c.
Chem. Abstract 86-29868a.
Kompis Ivan
Locher Rita
Maag Hans
Boxer Matthew
Goldberg Jerome D.
Hoffmann-La Roche Inc.
Leon Bernard S.
Saxe Jon S.
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