Pyrimidine derivatives for the treatment of abnormal cell...

Details Pyrimidine derivatives for the treatment of abnormal cell... Pyrimidine derivatives for the treatment of abnormal cell...

2006-12-20

2010-10-26

Rao, Deepak (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S235800, C514S252140, C514S252190, C514S275000, C540S581000, C544S122000, C544S295000, C544S323000, C544S324000

Reexamination Certificate

active

07820648

ABSTRACT:
The present invention relates to a compound of the formula 1or a pharmaceutically acceptable salt thereof, wherein Ar is a group of formulaand R1, R2, R13, A, K, M, L1, L2, X, Y1, Y2, Q, salt thereof, wherein R1, R2, R13, A, K, L1, L2, W, X, Z1, Z2, Y1, Y2, Z1, Z2, M, Q, W, X, m, p and q are as defined herein. Such novel pyrimidine derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. The invention also relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.

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