Pyrimidine derivatives for the treatment of abnormal cell...

Details Pyrimidine derivatives for the treatment of abnormal cell... Pyrimidine derivatives for the treatment of abnormal cell...

2006-09-19

2006-09-19

Balasubramanian, Venkataraman (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C544S324000, C514S275000

Reexamination Certificate

active

07109335

ABSTRACT:
The present invention relates to a compound of the formula 1wherein R1–R4are as defined herein. Such novel pyrimidine derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.

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