Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2005-10-04
2005-10-04
Wilson, James O. (Department: 1623)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C536S022100, C536S023100, C536S025300, C536S025310, C536S025320, C536S025340, C536S025400, C536S025330, C435S006120, C435S087000, C435S090000, C544S242000, C544S245000, C544S249000
Reexamination Certificate
active
06951931
ABSTRACT:
Compounds having structure (1)wherein R1is —H a protecting group, a linker or a binding partner; and R2and R34are as defined in the specification. The invention also provides intermediates and methods make the structure (1) compounds, as well as methods to use the compounds as labels in diagnostic assays and to enhance binding to complementary bases.
REFERENCES:
patent: 4233402 (1980-11-01), Maggio et al.
patent: 5286717 (1994-02-01), Cohn et al.
patent: 5502177 (1996-03-01), Matteucci et al.
patent: 5594121 (1997-01-01), Froehler et al.
patent: 5614617 (1997-03-01), Cook et al.
patent: 5614622 (1997-03-01), Iyer et al.
patent: 5623068 (1997-04-01), Reddy et al.
patent: 5645985 (1997-07-01), Froehler et al.
patent: 5668272 (1997-09-01), Prasad et al.
patent: 5728528 (1998-03-01), Mathies et al.
patent: 6028183 (2000-02-01), Lin et al.
patent: 6414127 (2002-07-01), Lin et al.
patent: 6800743 (2004-10-01), Lin et al.
patent: 0 487 289 (1992-05-01), None
patent: 0 541 153 (1993-05-01), None
patent: 62-059293 (1987-03-01), None
patent: WO 88/10264 (1988-12-01), None
patent: WO 90/15065 (1990-12-01), None
patent: WO 91/06626 (1991-05-01), None
patent: WO 91/06629 (1991-05-01), None
patent: WO 92/02258 (1992-02-01), None
patent: WO 92/20702 (1992-11-01), None
patent: WO 93/10820 (1993-06-01), None
patent: WO 93/13121 (1993-07-01), None
patent: WO 93/24507 (1993-12-01), None
patent: WO 96/05298 (1996-02-01), None
patent: WO 96/37504 (1996-11-01), None
patent: WO 97/14706 (1997-04-01), None
patent: WO 97/28176 (1997-08-01), None
patent: WO 97/31008 (1997-08-01), None
patent: WO 97/32880 (1997-09-01), None
patent: WO 97/32888 (1997-09-01), None
Bell, et al., “Highly Effective Hydrogen-Bonding Receptors for Guanine Derivatives”,Angew. Chem. Int. Ed., 1995, 44(19), 2163-2165.
Dande, et al., “Regioselective Effect of Zwitterionic DNA Substitutions on DNA Alkylation: Evidence for a Strong Side Chain Orientational Preference”,Biochem., 1997, 36, 6024-6023.
Haginoya et al., “Nucleosides and Nucleotides. 160. Synthesis of Oligodeoxyribonucleotides Containing 5-(N-Aminoalkyl)carbamoyl-2′-deoxyuridines by a New Postsynthetic Modification Method and Their Thermal Stability and Nuclease-Resistance Properties”,Bioconj. Chem., 1997, 8, 271-280.
Lin et al., “Tricyclic 2′-Deoxycytidine Analogs: Synthesis and Incorporation into Oligodeoxynucleotides Which Have Enhanced Binding to Complementary RNA”,J. Am. Chem. Soc., 1995, 117, 3873-3874.
Matteucci et al., “In pursuit of antisense”,Nature, 1996, 384(7), 20-22.
Prober et al., “A System for Rapid DNA Sequencing with Fluorescent Chain-Terminating Dideoxynucleotides”,Science, 1987, 238, 336-341.
Ueno et al., “Effects of 5-(N-aminohexyl)carbamoyl-2′-deoxyuridine on endonuclease stability and the ability of oligodeoxynucleotide to activate Rnase H”,Nucl. Acids Res., 1997, 25(19), 3777-3782.
Uhlmann et al., “Antisense Oligonucleotides: A New Therapeutic Principle”,Chem. Rev., 1990, 90(4), 543-584.
Lin Kuei-Ying
Matteucci Mark D.
Isis Patent Department
ISIS Pharmaceuticals Inc.
Lewis Patrick T.
Wilson James O.
Woodcock & Washburn LLP
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