Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1994-04-28
1996-05-28
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514272, 544295, 544322, 544331, 544332, C07D23992, A61K 31505
Patent
active
055211844
ABSTRACT:
There are described N-phenyl-2-pyrimidine-amine derivatives of formula I ##STR1## wherein R.sub.1 is 4-pyrazinyl, 1-methyl-1H-pyrrolyl, amino- or amino-lower alkyl-substituted phenyl wherein the amino group in each case is free, alkylated or acylated, 1H-indolyl or 1H-imidazolyl bonded at a five-membered ring carbon atom, or unsubstituted or lower alkyl-substituted pyridyl bonded at a ring carbon atom and unsubstituted or substituted at the nitrogen atom by oxygen, R.sup.2, R.sup.3, R.sup.9, X, Y, n and R.sup.10 are defined in claim 1
These compounds can be used, for example, in the therapy of tumoral diseases.
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patent: 4876252 (1989-10-01), Torley et al.
patent: 4940712 (1990-07-01), Walker et al.
90-231199/30 Derwent Abstract (1990) 1990 Corresponding to U.S. Pat. No. 4,940,712--Pfizer Inc.
89-167195 Derwent Abstract (1989) corresponding to EP 319,170--Pfizer Inc.
Ciba-Geigy Corporation
Grumbling Matthew V.
Kaiser Karen G.
Shah Mukund J.
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