Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-02-11
1995-03-14
Ford, John M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
5142322, 5142358, 514252, 514269, 514270, 514272, 514273, 514274, 514275, 544322, 544300, 544301, 544310, 544311, 544316, 544317, 544319, 544320, 544321, 544323, 544324, 544295, 544122, 544123, 544 82, A61K 31505, C07D23942, C07D23950, C07D23948
Patent
active
053977815
ABSTRACT:
The present invention relates to novel 5-(.omega.-substituted amino-alkanoyl amino)pyrimidine derivatives, processes for producing the derivatives, and pharmaceutical compositions containing said derivatives. The compounds in the present invention have potent effects of inhibiting ACAT activity and lowering serum cholesterol. The compounds of the present invention are extremely useful for the treatment and/or prevention of arteriosclerosis or hyperlipidemia.
REFERENCES:
Bell et al., Chemical Abstracts, vol. 56, entry 12894f (1962).
Weinstock et al., Chemical Abstracts, vol. 73, entry 110105c (1970).
Bell et al. J. Org. Chem., vol. 26, 1961, pp. 3534-3535.
Mizuguchi Kiyoshi
Murakami Kimihiro
Ohnishi Shuhei
Yanagibashi Kazutoshi
Ford John M.
Mochida Pharmaceutical Company, Limited
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