Pyrimidine derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C544S250000

Reexamination Certificate

active

10491680

ABSTRACT:
Pyrimidine derivatives of the formula (I) and physiologically acceptable salts thereof, in which R1, R2, R3, R4, W, X, Y and Z are as defined in claim1,exhibit phosphodiesterase V inhibition and can be employed for the treatment of diseases of the cardiovascular system and for the treatment and/or therapy of potency disorders

REFERENCES:
patent: 3037980 (1962-06-01), Hitchings et al.
patent: 4007187 (1977-02-01), Fauran et al.
patent: 0 046 677 (1982-03-01), None
patent: 0 514 540 (1992-11-01), None
patent: 0 728 759 (1996-08-01), None
patent: 98 17668 (1998-04-01), None
patent: 99 28325 (1999-06-01), None
patent: 99 55708 (1999-11-01), None
patent: 99 62518 (1999-12-01), None
patent: WO 99 62518 (1999-12-01), None
patent: 01 18004 (2001-03-01), None
patent: 01 21620 (2001-03-01), None
patent: 01 39777 (2001-06-01), None
patent: WO 01/39777 (2001-06-01), None
patent: 02 057267 (2002-07-01), None
West, Anthony R., Solid State Chemistry and Its Applications, Wiley, New York (1988).
Meade, et al., Anxiolytic Activity of Analogues of 4-benzylamino-2-methyl-7H-pyrrolo[2,3-d]pyrimidines, Eur. J. Med. Chem., pp. 363-374, vol. 33 (1998).
Campbell, et al., Selective A1-adenosine Receptor Antagonists Identified Using YeastSaccharomyces cerevisiaeFunctional Assays, Bioorganic & Medicinal Chemistry Letters, 9, 2413-2418 (1999).
Chemical Abstracts No. 48031, vol. 80, No. 9 (Mar. 4, 1974).
Chemical Abstracts No. 82224, vol. 82, No. 13 (Mar. 31, 1975).
Chemical Abstracts No. 126924, vol. 76, No. 21 (May 22, 1972).
Chemical Abstracts, vol. 63, No. 11 (1965).
Chemical Abstracts No. 97174, vol. 111, No. 11 (Sep. 11, 1989).
Chemical Abstracts No. 112617, vol. 123, No. 9 (Aug. 28, 1995).
Chemical Abstracts No. 79191, vol. 83, No. 9 (Sep. 1, 1975).
R. Campbell, et al., “Selective A1-Adenosine Receptor . . . Functional Assays”,Bioorganic&Medicinal Chemistry Letters, Bd. 9, Nr. 16 (Aug. 16, 1999).
E. Meade, et al., “Anxiolytic Activity . . . pyrimidines”,European Journal of Medicinal Chemistry, Bd. 33, Nr. 5, (Jun. 1, 1998).
West, et al., “2-Alkyl(aryl) . . . pyrimidines”,J. Org. Chem, Bd. 26 (1961).
Lockhart et al., “Synthesis of Subtituted furo . . . ”,J. Heterocyclic Chem, Bd. 33, Nr. 3 (1996).
J-P Marquet et al., “Furannes et Pyrroles . . . 4-Substitut”,Bulletin de la Societe Chimique de France, Nr. 12 (1969).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Pyrimidine derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pyrimidine derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pyrimidine derivatives will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3893819

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.