Pyrimidine derivatives

Details Pyrimidine derivatives Pyrimidine derivatives

1992-06-12

1993-11-09

Ford, John M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

544316, 544318, C07D23934, C07D23938, C07D23942

Patent

active

052604403

ABSTRACT:
The compounds of the present invention inhibit the HMG-CoA reductase, and subsequently suppress the biosynthesis of cholesterol. And they are useful in the treatment of hypercholesterolemia, hyperlipoproteinemia, and atherosclerosis.

REFERENCES:
Moore et al., J. Am. Chem. Soc. vol. 107, pp. 3694-3701 (1985).

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