Pyrimidine compounds having activity as a cardiotonic anti-hyper

Details Pyrimidine compounds having activity as a cardiotonic anti-hyper Pyrimidine compounds having activity as a cardiotonic anti-hyper

1985-07-05

1988-02-16

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514252, 514254, 514258, 514272, 514274, 544263, 544295, 544315, 544316, 544317, 544318, 544319, 544320, 544322, 544323, 544324, 544325, 544326, A61K 31495, C07D40304, C07D23924

Patent

active

047256001

ABSTRACT:
The invention relates to pyrimidine compounds of the formula: ##STR1## wherein the substituents R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 are as herein defined, having activity as a cardiotonic, anti-hypertensive, cerebrovascular vasodilator and anti-platelet aggregation agent.

REFERENCES:
patent: 3707560 (1972-12-01), De Angelis et al.
patent: 3859288 (1975-01-01), De Angelis et al.
patent: 3908012 (1975-09-01), De Angelis et al.
patent: 3950525 (1976-04-01), De Angelis et al.
patent: 4450162 (1984-05-01), Kamioka et al.
Brown et al., Chemical Abstracts, vol. 74:75908p, 1971.
Ursprung et al., Chemical Abstracts, vol. 70:115172v, 1969.

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