Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-10-11
2005-10-11
Rotman, Al (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S235500, C514S235800, C514S252100, C514S252140, C514S252180, C514S252190, C514S252200, C514S255050, C514S269000, C544S121000, C544S122000, C544S296000, C544S319000
Reexamination Certificate
active
06953803
ABSTRACT:
Pyrmidinone compounds of formula (I)are inhibitors of the enzyme Lp-PLA2and of use in therapy, in particular for treating atherosclerosis.
REFERENCES:
patent: 1 582 527 (1981-01-01), None
patent: WO 99/24420 (1999-05-01), None
patent: WO 00/10980 (2000-03-01), None
Blackie, J.A. et. al., “The Discovery of SB-435495 . . . ”, Bioorganic & Medicinal Chemistry Letters, (2002), vol. 12, No. 18, pp. 2603-2606.
Hickey Deirdre Mary Bernadette
Leach Colin Andrew
Smith Stephen Allan
Kanagy James M.
Kinzig Charles M.
Rotman Al
SmithKline Beecham p.l.c.
Truong Tamthom N.
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