Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2008-07-08
2008-07-08
Shiao, Rei-tsang (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C544S330000, C544S331000, C544S332000, C544S333000
Reexamination Certificate
active
10492905
ABSTRACT:
A compound having excellent adenosine receptor (A1, A2A, A2Breceptor) antagonistic action, of the following formula, a salt thereof or a solvate of them:wherein, R1and R2, same or different, each represents a hydrogen atom, an alkyl group, an alkenyl group, an alkynyl group, a cycloalkyl group, a cycloalkenyl group, an aromatic hydrocarbon cyclic group, an acyl group or an alkylsulfonyl group, which groups may be substituted (except the hydrogen atom); R3represents a hydrogen atom, a halogen atom, a cyano group, an alkyl group, an alkenyl group, an alkynyl group, an aromatic hydrocarbon cyclic group, a nitrogen atom, an oxygen atom or a sulfur atom, which groups may be substituted (except the hydrogen atom, the halogen atom and the cyano group); R4represents an aromatic hydrocarbon cyclic group which may be substituted, and R5represents an aromatic hydrocarbon cyclic group which may be substituted.
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Harada Hitoshi
Iida Daisuke
Kotake Yoshihiko
Nagakawa Junichi
Nakagawa Makoto
Eisai R&D Management Co., Ltd.
Shiao Rei-tsang
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