Pyrimidine carboxylates and related compounds and methods for tr

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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544331, 544332, C07D23902, A01N 4354

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active

059359668

ABSTRACT:
Compounds having utility as anti-inflammatory agents in general and, more specifically, for the prevention and/or treatment of immunoinflammatory and autoimmune diseases are disclosed. The compounds are pyrimidine-containing compounds and, in one embodiment, are esters of the same. Methods are also disclosed for preventing and/or treating inflammatory conditions by administering to an animal in need thereof an effective amount of a compound of this invention, preferably in the form of a pharmaceutical composition.

REFERENCES:
patent: 3670077 (1972-06-01), Freeman et al.
patent: 3814762 (1974-06-01), Santilli et al.
patent: 5703106 (1997-12-01), Fruh et al.
Assy et al., "Some reactions with ethyl 4-(mercapto/chloro)-6-methyl-2-phenylpyrimidine-5-carboxylate," Chemical Abstracts 125(5): p. 1148, Abstract No. 58437p, 1996.

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