Pyrimidine and s-triazine derivatives with antilipidemic activit

Details Pyrimidine and s-triazine derivatives with antilipidemic activit Pyrimidine and s-triazine derivatives with antilipidemic activit

1982-07-21

1985-12-17

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544320, 544312, 544317, 544321, 544323, 544197, 544208, 544211, 544204, 544210, 544194, 544213, C07D23946, C07D23948, C07D25118, A61K 31505

Patent

active

045593450

ABSTRACT:
Pyrimidine and s-triazine derivatives of formula (I) ##STR1## in which X=CH or N; Y=for example halogen, alkoxy; W=for example --S--CH.sub.2 --COOH, --O--CH.sub.2 --COO alkyl, --NH--CH.sub.2 --CONHCH.sub.2 CH.sub.2 OH; Z=for example 2,3-xylidino, and methods for the preparation thereof are described. The compounds show high antilipemic activity.

REFERENCES:
patent: 3321478 (1967-05-01), English et al.
patent: 3609136 (1971-09-01), Wegmuller et al.
patent: 3814761 (1974-06-01), Santilli et al.
patent: 3974162 (1976-08-01), Santilli et al.
Reddy et al., Chem. Abstracts, 92:175480h, (1980).
Reddy et al., Chem. Abstracts, 84:38736s, (1976).

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