Pyridylketoxime ether compound and pharmaceutical composition co

Details Pyridylketoxime ether compound and pharmaceutical composition co Pyridylketoxime ether compound and pharmaceutical composition co

1989-10-19

1990-11-20

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514323, 514332, 514336, 514338, 546236, 546264, 546270, 546283, 546284, 546334, A61K 3144, C07D21354

Patent

active

049719858

ABSTRACT:
A pyridylketoxime ether compound of the formula: ##STR1## wherein Ar is a phenyl, naphthyl, or heterocyclic group unsubstituted or substituted by a C.sub.1 -C.sub.8 alkyl group, a C.sub.1 -C.sub.8 alkylamino group, a C.sub.1 -C.sub.8 alkoxy group, a C.sub.1 -C.sub.8 alkoxycarbonyl group, a trifluoromethyl group, a nitro group or a halogen atom, X is a --(CH.sub.2).sub.m -- group wherein m is an integer of from 1 to 5, a --(CH.sub.2).sub.m --Y-- group wherein Y is an oxygen or sulfur atom and m is as defined above, or a --CH.sub.2 --(CH.dbd.CH).sub.n -- group wherein n is an integer of 1 or 2, and R is a phenyl, naphthyl, C.sub.3 -C.sub.8 cycloalkyl or heterocyclic group unsubstituted or substituted by a C.sub.1 -C.sub.8 alkyl group, a C.sub.1 -C.sub.8 alkylamino group, a C.sub.1 -C.sub.8 alkoxy group, a C.sub.1 -C.sub.8 akloxycarbonyl group, a trifluoromethyl group, a nitro group or a halogen atom, or a salt thereof.

REFERENCES:
patent: 4297359 (1981-10-01), van Zorge
patent: 4352804 (1982-10-01), van Zorge
Chemical Abstracts, vol. 90, No. 13, Mar. 1979, U.S.A., Tankaka et al., Abstract No. 103840m.
Chemical Abstracts, vol. 111, No. 9, Abstract 70,646z. Aug. 28, 1989, p. 51.

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