Pyridylalkyl esters of 2-(p-isobutylphenyl)acetic acid and propi

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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26032643, 2603474, 42424855, 424250, 424267, 424274, 424285, 424308, 544171, 544399, 546238, 546342, 560105, A61K 3144, C07D21355

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041501373

ABSTRACT:
The present invention relates to phenylacetic acid ester derivatives of the following general formula: ##STR1## wherein, R is selected from the group consisting of lower alkyl (other than ethyl) and substituted lower alkyl, and R' may be a hydrogen or methyl.
The compounds obtained by the present invention possess a high degree of analgetic ,antipyretic and anti-inflammatory activites and cause little side effects on the gastro-intestinal tracts, when administered orally and topically, and they may be useful as oral and topical analgetics, antipyretics and antiinflammatory agents.

REFERENCES:
patent: 3228831 (1966-01-01), Nicolson et al.
Nakanishi et al., Chem. Abst., vol. 84, 1975, parag. 105414a.

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