Pyridyl derivatives and their use as therapeutic agents

Details Pyridyl derivatives and their use as therapeutic agents Pyridyl derivatives and their use as therapeutic agents

2004-07-29

2009-10-20

Wilson, James O (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C544S358000

Reexamination Certificate

active

07605161

ABSTRACT:
Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a mammal in need thereof a compound of formula (I): wherein: W is —O—, —N(R1)—, C(O), S(O)t; (where t is 0, 1 or 2), N(R1)S(O)2, S(O)2N(R1), C(O)N(R1) or N(R1)C(O)N(R1); and V is C(O), C(S), C(O)N(R1)—, C(O)O—, S(O)2—, S(O)2N(R1)— or C(R11)H; and x, y, R1, R2, R3, R4, R5, R6, R7, R7a, R8, R8a, R9, R9a, R10 and R10aare defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.

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