Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1983-03-09
1985-11-05
Fan, Jane T.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514343, 514340, 546276, 546193, C07D40112, C07D40114, A61K 31445
Patent
active
045514666
ABSTRACT:
This invention relates to diaminotriazole derivatives in which one amino group is substituted by a 4-dialkylamino- or piperidinyl- or pyrolidinylmethyl pyrid-2-yloxypropyl group. The compounds have histamine H.sub.2 -antagonist activity. One specific compound is 1-methyl-N.sup.5 -3-(4-[1-piperidinomethyl]-pyridyl-2-oxy)-propyl-1H-1,2,4-triazole-3,5-dia mine.
REFERENCES:
patent: 4252819 (1981-02-01), Hirata et al.
patent: 4318913 (1982-03-01), Clitherow et al.
patent: 4411899 (1983-10-01), Baldwin et al.
Derwent Abstract 29067E (EP 49173).
Derwent Abstract 20656D (Netherlands 8004967).
Derwent Abstract 269K (EP 67436).
Cooper David G.
Sach George S.
Fan Jane T.
Foggio Richard D.
Keps Joan S.
Lourie Alan D.
Smith Kline & French Laboratories Limited
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