Pyridoxal-5'-phosphate as an in vitro blood platelet stabilizer

Details Pyridoxal-5'-phosphate as an in vitro blood platelet stabilizer Pyridoxal-5'-phosphate as an in vitro blood platelet stabilizer

1990-06-04

1993-05-25

Rosen, Sam

Drug, bio-affecting and body treating compositions

Extract, body fluid, or cellular material of undetermined...

Blood

424529, 424530, 435 2, A61K 3514

Patent

active

052138135

ABSTRACT:
The use of pyridoxal-5'-phosphate as an in vitro anticoagulant agent which retains the platelet activity of stored whole blood or stored plasma for more than about six hours is disclosed.

REFERENCES:
Kornecki et al.-Am. J. Physiology vol. 238(1) (1980) pp. H54-H60.
Krischnamurthi et al.-Thrombosis Haemostasis-vol. 48(2) (1982) pp. 136-141.
Kornecki et al.-Chem. Abst. vol. 92 (1980) pp. 104, 120e.
Krischnamurthi et al.-Chem. Abst. vol. 98 (1983), p. 51127c.
Kornecki-Chem. Abst. vol. 93 (1980) p. 487j.
Pyridoxal-5'-Phosphate Inhibition of Platelet Function, Ph.D. Thesis Elizabeth Korneck, University of Illinois (1979).

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