Pyridopyrimidinone derivatives which are HM74A agonists

Details Pyridopyrimidinone derivatives which are HM74A agonists Pyridopyrimidinone derivatives which are HM74A agonists

2007-05-11

2009-08-11

Berch, Mark L (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S264110, C544S279000, C546S316000

Reexamination Certificate

active

07572801

ABSTRACT:
The invention is concerned with novel pyridopyrimidinone derivatives of formula (I):wherein R1to R8, X, Y, m and n are as defined in the description and in the claims. The compounds of the present invention are HM74A agonists with improved properties compared to niacin and can be used for the treatment and/or prevention of diseases such as dyslipidemia, atherosclerosis, diabetes, metabolic syndrome, and other related diseases associated with HM74A.

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